I have designed a remote crystal-centering software package that now allows synchrotron beamline users to position protein crystals in the x-ray beam with a few clicks of the mouse. The high-resolution display uses state-of-the art streaming digital video that can be viewed on any computer console outside the experimental hutch, including remote sites. The system has been in operation during the past year. The current system is not only faster than manual positioning, but also more accurate, allowing smaller protein crystals to be rapidly positioned for structural studies.
In addition, we now are working on image recognition algorithms that will detect and center crystals in real-time. We are working towards having the first completely automated crystal mounting and centering system
- Ismail Degani
Read the paper draft
See the hutch setup
